New tamoxifen analogs for breast cancer therapy: synthesis, aromatase inhibition and <i>in silico</i> studies.

Al-Kelabi, Hasan; Al-Duhaidahawi, Dunya; Al-Khafaji, Khattab; Al-Masoudi, Najim A

New tamoxifen analogs for breast cancer therapy: synthesis, aromatase inhibition and in silico studies.

Al-Kelabi, Hasan; Al-Duhaidahawi, Dunya; Al-Khafaji, Khattab; Al-Masoudi, Najim A.

Afiliação

Al-Kelabi H; Pharmacy Department, AL-Najaf Health Directorate, Ministry of Health, Najaf, Iraq.
Al-Duhaidahawi D; Department of Pharmacognosy, College of Pharmacy, University of Kufa Al-Najaf, Kufa, Iraq.
Al-Khafaji K; Pharmacy Department, Al-Maarif University College, Anbar, Iraq.
Al-Masoudi NA; Department of Chemistry, College of Science, University of Basrah, Basrah, Iraq.

J Biomol Struct Dyn ; 41(22): 12798-12807, 2023.

Article em En | MEDLINE | ID: mdl-36762686

Assuntos

Neoplasias da Mama; Tamoxifeno; Gravidez; Feminino; Humanos; Tamoxifeno/farmacologia; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/metabolismo; Inibidores da Aromatase/farmacologia; Aromatase; Receptores de Estrogênio; Placenta/metabolismo; Proliferação de Células

Palavras-chave

Aromatase inhibitors; breast cancer; estrogen receptor (ER+); ketoprofen; molecular modelling study; tamoxifen analogues

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama Limite: Female / Humans / Pregnancy Idioma: En Revista: J Biomol Struct Dyn Ano de publicação: 2023 Tipo de documento: Article

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