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Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial.
Sanyal, Arun J; Lopez, Patricia; Lawitz, Eric J; Lucas, Kathryn J; Loeffler, Juergen; Kim, Won; Goh, George B B; Huang, Jee-Fu; Serra, Carla; Andreone, Pietro; Chen, Yi-Cheng; Hsia, Stanley H; Ratziu, Vlad; Aizenberg, Diego; Tobita, Hiroshi; Sheikh, Aasim M; Vierling, John M; Kim, Yoon Jun; Hyogo, Hideyuki; Tai, Dean; Goodman, Zachary; Schaefer, Felicity; Carbarns, Ian R I; Lamle, Sophie; Martic, Miljen; Naoumov, Nikolai V; Brass, Clifford A.
Afiliação
  • Sanyal AJ; Virginia Commonwealth University School of Medicine, Richmond, VA, USA. arun.sanyal@vcuhealth.org.
  • Lopez P; Novartis Pharma AG, Basel, Switzerland.
  • Lawitz EJ; Texas Liver Institute, University of Texas Health, San Antonio, TX, USA.
  • Lucas KJ; Diabetes and Endocrinology Consultants, Morehead City, NC, USA.
  • Loeffler J; Novartis Pharma AG, Basel, Switzerland.
  • Kim W; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Republic of Korea.
  • Goh GBB; Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore, Singapore.
  • Huang JF; Hepatitis Centre and Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung City, Taiwan.
  • Serra C; Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS, Azienda Ospedaliero-Universitaria, Bologna, Italy.
  • Andreone P; University of Modena and Reggio Emilia, Modena, Italy.
  • Chen YC; Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.
  • Hsia SH; Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
  • Ratziu V; National Research Institute, Los Angeles, CA, USA.
  • Aizenberg D; Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Hôpital Pitié Salpêtrière, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France.
  • Tobita H; Centro Medico Viamonte, Buenos Aires, Argentina.
  • Sheikh AM; Shimane University Hospital, Izumo, Japan.
  • Vierling JM; Gastrointestinal Specialists of Georgia, Marietta, GA, USA.
  • Kim YJ; Advanced Liver Therapies, Baylor College of Medicine, Houston, TX, USA.
  • Hyogo H; Seoul National University College of Medicine and Liver Research Institute, Seoul, Korea.
  • Tai D; JA Hiroshima General Hospital, Hiroshima, Japan.
  • Goodman Z; Life Care Clinic Hiroshima, Hiroshima, Japan.
  • Schaefer F; HistoIndex Pte. Ltd, Singapore, Singapore.
  • Carbarns IRI; Inova Fairfax Hospital, Falls Church, VA, USA.
  • Lamle S; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA.
  • Martic M; Novartis Pharma AG, Basel, Switzerland.
  • Naoumov NV; Novartis Pharma AG, Basel, Switzerland.
  • Brass CA; Novartis Pharma AG, Basel, Switzerland.
Nat Med ; 29(2): 392-400, 2023 02.
Article em En | MEDLINE | ID: mdl-36797481
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Nat Med Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: Nat Med Ano de publicação: 2023 Tipo de documento: Article