Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-ðB-IL-6 axis of tumor-associated macrophages.

Zhou, Boxuan; Mo, Zhaohong; Lai, Guie; Chen, Xiaohong; Li, Ruixi; Wu, Runxin; Zhu, Jia; Zheng, Fang

Targeting tumor exosomal circular RNA cSERPINE2 suppresses breast cancer progression by modulating MALT1-NF-ðB-IL-6 axis of tumor-associated macrophages.

Zhou, Boxuan; Mo, Zhaohong; Lai, Guie; Chen, Xiaohong; Li, Ruixi; Wu, Runxin; Zhu, Jia; Zheng, Fang.

Afiliação

Zhou B; Department of Breast Surgery, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.
Mo Z; Medical Research Center and Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, 510120, China.
Lai G; Department of Hepatobiliary Surgery, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510630, China.
Chen X; Department of Breast Surgery, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.
Li R; Department of Laboratory, the First Affiliated Hospital of Gannan Medical University, Ganzhou, 341000, China.
Wu R; Department of Hepatobiliary and Pancreatic Surgery, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518033, China.
Zhu J; Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
Zheng F; Department of Breast Surgery, the First Affiliated Hospital of Nanchang University, Nanchang, 330000, China. Zhujia888618@163.com.

J Exp Clin Cancer Res ; 42(1): 48, 2023 Feb 17.

Article em En | MEDLINE | ID: mdl-36797769

Assuntos

Neoplasias da Mama; RNA Circular; Feminino; Humanos; Neoplasias da Mama/tratamento farmacológico; Neoplasias da Mama/genética; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Proliferação de Células; Interleucina-6/metabolismo; Macrófagos/metabolismo; Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa/metabolismo; RNA Circular/genética; RNA Circular/metabolismo; Serpina E2/metabolismo; Serpina E2/farmacologia; Microambiente Tumoral; Macrófagos Associados a Tumor/metabolismo; Animais

Palavras-chave

Breast cancer; Exosome; Nanoparticles; Tumor-associated macrophages; cSERPINE2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / RNA Circular Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: J Exp Clin Cancer Res Ano de publicação: 2023 Tipo de documento: Article

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