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Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Afroz, Tariq; Chevalier, Elodie; Audrain, Mickael; Dumayne, Christopher; Ziehm, Tamar; Moser, Roger; Egesipe, Anne-Laure; Mottier, Lorène; Ratnam, Monisha; Neumann, Manuela; Havas, Daniel; Ollier, Romain; Piorkowska, Kasia; Chauhan, Mayank; Silva, Alberto B; Thapa, Samjhana; Stöhr, Jan; Bavdek, Andrej; Eligert, Valerie; Adolfsson, Oskar; Nelson, Peter T; Porta, Sílvia; Lee, Virginia M-Y; Pfeifer, Andrea; Kosco-Vilbois, Marie; Seredenina, Tamara.
Afiliação
  • Afroz T; AC Immune SA, Lausanne, Switzerland. Electronic address: tariq.afroz@acimmune.com.
  • Chevalier E; AC Immune SA, Lausanne, Switzerland.
  • Audrain M; AC Immune SA, Lausanne, Switzerland.
  • Dumayne C; AC Immune SA, Lausanne, Switzerland.
  • Ziehm T; AC Immune SA, Lausanne, Switzerland.
  • Moser R; AC Immune SA, Lausanne, Switzerland.
  • Egesipe AL; AC Immune SA, Lausanne, Switzerland.
  • Mottier L; AC Immune SA, Lausanne, Switzerland.
  • Ratnam M; AC Immune SA, Lausanne, Switzerland.
  • Neumann M; Department of Neuropathology, University of Tübingen, Tübingen, Germany; DZNE, German Center for Neurodegenerative Diseases, Tübingen, Germany.
  • Havas D; Psychogenics Inc., Paramus, NJ, USA.
  • Ollier R; AC Immune SA, Lausanne, Switzerland.
  • Piorkowska K; AC Immune SA, Lausanne, Switzerland.
  • Chauhan M; AC Immune SA, Lausanne, Switzerland.
  • Silva AB; AC Immune SA, Lausanne, Switzerland.
  • Thapa S; AC Immune SA, Lausanne, Switzerland.
  • Stöhr J; AC Immune SA, Lausanne, Switzerland.
  • Bavdek A; AC Immune SA, Lausanne, Switzerland.
  • Eligert V; AC Immune SA, Lausanne, Switzerland.
  • Adolfsson O; AC Immune SA, Lausanne, Switzerland.
  • Nelson PT; University of Kentucky, Lexington, KY, USA.
  • Porta S; Center for Neurodegenerative Disease Research (CNDR), Institute on Aging, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Lee VM; Center for Neurodegenerative Disease Research (CNDR), Institute on Aging, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Pfeifer A; AC Immune SA, Lausanne, Switzerland.
  • Kosco-Vilbois M; AC Immune SA, Lausanne, Switzerland.
  • Seredenina T; AC Immune SA, Lausanne, Switzerland. Electronic address: tamara.seredenina@acimmune.com.
Neurobiol Dis ; 179: 106050, 2023 04.
Article em En | MEDLINE | ID: mdl-36809847
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Pick / Demência Frontotemporal / Doença de Alzheimer / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Pick / Demência Frontotemporal / Doença de Alzheimer / Esclerose Lateral Amiotrófica Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Neurobiol Dis Ano de publicação: 2023 Tipo de documento: Article