Bioprocess Development and Characterization of a <sup>13</sup>C-Labeled Hybrid Bispecific Antibody Produced in <i>Escherichia coli</i>.

Wecksler, Aaron T; Lundin, Victor; Williams, Ambrose J; Veeravalli, Karthik; Reilly, Dorothea E; Grieco, Sung-Hye

Bioprocess Development and Characterization of a ¹³C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli.

Wecksler, Aaron T; Lundin, Victor; Williams, Ambrose J; Veeravalli, Karthik; Reilly, Dorothea E; Grieco, Sung-Hye.

Afiliação

Wecksler AT; Protein Analytical Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.
Lundin V; Protein Analytical Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.
Williams AJ; Purification Development, Genentech Inc., South San Francisco, CA 94080, USA.
Veeravalli K; Cell Culture and Bioprocess Operations, Genentech Inc., South San Francisco, CA 94080, USA.
Reilly DE; Cell Culture and Bioprocess Operations, Genentech Inc., South San Francisco, CA 94080, USA.
Grieco SH; Cell Culture and Bioprocess Operations, Genentech Inc., South San Francisco, CA 94080, USA.

Antibodies (Basel) ; 12(1)2023 Feb 14.

Article em En | MEDLINE | ID: mdl-36810521

Palavras-chave

13C-celtone; 13C-labeled glucose; ambr250 bioreactors; biotherapeutic proteins; knob-into-hole; protein isotopic labeling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antibodies (Basel) Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Antibodies (Basel) Ano de publicação: 2023 Tipo de documento: Article