Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment.

Chen, Juntao; Xu, Cuidi; Yang, Kun; Gao, Rifeng; Cao, Yirui; Liang, Lifei; Chen, Siyue; Xu, Shihao; Rong, Ruiming; Wang, Jina; Zhu, Tongyu

Chen, Juntao; Xu, Cuidi; Yang, Kun; Gao, Rifeng; Cao, Yirui; Liang, Lifei; Chen, Siyue; Xu, Shihao; Rong, Ruiming; Wang, Jina; Zhu, Tongyu.

Afiliação

Chen J; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xu C; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Yang K; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Gao R; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Cao Y; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Liang L; The Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China.
Chen S; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Xu S; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Rong R; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Wang J; Shanghai Key Laboratory of Organ Transplantation, Shanghai, China.
Zhu T; Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.

Nat Commun ; 14(1): 1161, 2023 03 01.

Article em En | MEDLINE | ID: mdl-36859428

Assuntos

Injúria Renal Aguda; Homólogo AlkB 5 da RNA Desmetilase; Quimiocinas CC; Linfócitos T Reguladores; Animais; Masculino; Camundongos; Rim/fisiologia; Camundongos Knockout; Homólogo AlkB 5 da RNA Desmetilase/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T Reguladores / Quimiocinas CC / Injúria Renal Aguda / Homólogo AlkB 5 da RNA Desmetilase Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Nat Commun Ano de publicação: 2023 Tipo de documento: Article

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