IL-1ß contributes to the secretion of sclerostin by osteocytes and targeting sclerostin promotes spinal fusion at early stages.

Jiang, Zengxin; Jin, Lixia; Jiang, Chang; Yan, Zuoqin; Cao, Yuanwu

Jiang, Zengxin; Jin, Lixia; Jiang, Chang; Yan, Zuoqin; Cao, Yuanwu.

Afiliação

Jiang Z; Department of Orthopaedics, Shanghai Sixth People's Hospital, Shanghai, 200233, China.
Jin L; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, NO. 180 Feng Lin Road, Xuhui District, Shanghai, 200032, China.
Jiang C; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, NO. 180 Feng Lin Road, Xuhui District, Shanghai, 200032, China.
Yan Z; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, NO. 180 Feng Lin Road, Xuhui District, Shanghai, 200032, China.
Cao Y; Department of Orthopedic Surgery, Zhongshan Hospital, Fudan University, NO. 180 Feng Lin Road, Xuhui District, Shanghai, 200032, China. yan.zuoqin@zs-hospital.sh.cn.

J Orthop Surg Res ; 18(1): 162, 2023 Mar 03.

Article em En | MEDLINE | ID: mdl-36864451

Assuntos

Calcinose; Fusão Vertebral; Animais; Ratos; Calcificação Fisiológica; Diferenciação Celular; Osteócitos; Osteogênese; Interleucina-1beta/farmacologia

Palavras-chave

IL-1ß; Osteoblast; Osteocyte; Sclerostin; Spinal fusion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fusão Vertebral / Calcinose Tipo de estudo: Guideline / Prognostic_studies Limite: Animals Idioma: En Revista: J Orthop Surg Res Ano de publicação: 2023 Tipo de documento: Article

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