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Proprioceptors-enriched neuronal cultures from induced pluripotent stem cells from Friedreich ataxia patients show altered transcriptomic and proteomic profiles, abnormal neurite extension, and impaired electrophysiological properties.
Dionisi, Chiara; Chazalon, Marine; Rai, Myriam; Keime, Céline; Imbault, Virginie; Communi, David; Puccio, Hélène; Schiffmann, Serge N; Pandolfo, Massimo.
Afiliação
  • Dionisi C; Laboratory of Experimental Neurology, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
  • Chazalon M; Laboratory of Neurophysiology, ULB-Neuroscience Institute (UNI), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
  • Rai M; Laboratory of Experimental Neurology, Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
  • Keime C; Institut de Génétique et de Biologie Moléculaire et Cellulaire UMR 7104 CNRS-UdS / INSERM U1258, Université de Strasbourg, 67404 Illkirch Cedex, Strasbourg, France.
  • Imbault V; Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
  • Communi D; Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
  • Puccio H; Institut de Génétique et de Biologie Moléculaire et Cellulaire UMR 7104 CNRS-UdS / INSERM U1258, Université de Strasbourg, 67404 Illkirch Cedex, Strasbourg, France.
  • Schiffmann SN; Institut NeuroMyoGene (INMG) UMR5310-INSERM U1217, Faculté de Médecine, Université Claude Bernard-Lyon I, 69008 Lyon, France.
  • Pandolfo M; Laboratory of Neurophysiology, ULB-Neuroscience Institute (UNI), Université Libre de Bruxelles (ULB), 1070 Brussels, Belgium.
Brain Commun ; 5(1): fcad007, 2023.
Article em En | MEDLINE | ID: mdl-36865673
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Brain Commun Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Brain Commun Ano de publicação: 2023 Tipo de documento: Article