Photocatalytic 1,2-Iminosulfonylation and Remote 1,6-Iminosulfonylation of Olefins.
Org Lett
; 25(10): 1742-1747, 2023 Mar 17.
Article
em En
| MEDLINE
| ID: mdl-36883883
ABSTRACT
A new class of iminosulfonylation reagents were developed and extensively used in the 1,2-iminosulfonylation of various olefins. Olefins containing bioactive molecules, such as indomethacin, gemfibrozil, clofibrate, and fenbufen, afforded the desired iminosulfonylation products in synthetically useful yields. Furthermore, the first remote 1,6-iminosulfonylation of alkenes was realized by using oxime ester bifunctionalization reagents. Overall, more than 40 structurally diverse ß-imine sulfones were obtained in moderate to excellent yields.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2023
Tipo de documento:
Article