A Case of Miller Fisher Syndrome with Cerebellar Hypoperfusion.
Tohoku J Exp Med
; 260(1): 47-50, 2023 May 17.
Article
em En
| MEDLINE
| ID: mdl-36889739
ABSTRACT
We report a case of a 76-year-old man with Miller Fisher syndrome presenting with acute ophthalmoplegia and ataxia. Cerebrospinal fluid analysis showed normocytosis with an increased protein level. Serum anti-GQ1b IgG and anti-GT1a IgG antibodies were positive. Based on these results, the patient was diagnosed with Miller Fisher syndrome. He was treated with two courses of intravenous immunoglobulin, which improved his neurological symptoms. Brain perfusion single-photon emission computed tomography showed that cerebellar blood flow was decreased in the acute stage of the disease and improved after treatment. Although the prevailing view is that ataxia in Miller Fisher syndrome patients is of a peripheral origin, this case suggests that cerebellar hypoperfusion contributes to the development of ataxia in Miller Fisher syndrome.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ataxia Cerebelar
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Oftalmoplegia
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Síndrome de Miller Fisher
Tipo de estudo:
Diagnostic_studies
Limite:
Aged
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Humans
/
Male
Idioma:
En
Revista:
Tohoku J Exp Med
Ano de publicação:
2023
Tipo de documento:
Article