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Behavioral characteristics in sensing mechanism of the Corti.
Liang, Junyi; Wang, Jiakun; Yao, Wenjuan; Zhou, Lei; Huang, Xinsheng.
Afiliação
  • Liang J; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44106, USA.
  • Wang J; Shanghai Institute of Applied Mathematics and Mechanics, Shanghai 200072, PR China.
  • Yao W; Shanghai Institute of Applied Mathematics and Mechanics, Shanghai 200072, PR China.
  • Zhou L; Department of Otorhinolaryngology, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China.
  • Huang X; Department of Otorhinolaryngology, Zhongshan Hospital, Fudan University, Shanghai 200032, PR China.
Comput Struct Biotechnol J ; 21: 1797-1806, 2023.
Article em En | MEDLINE | ID: mdl-36915377
ABSTRACT
Some experiments can't be realized because the cochlea's Corti is the most delicate and complex sensory organ. In this paper, some typical and special behavioral characteristics in the process of sensation were found in medical clinic. Based on the interdisciplinary principles of medicine, physics and biology, a real numerical simulation model of Corti is established. On the basis of verifying the correctness of the model, the mechanism corresponding to these typical and special behavior characteristics in the process of sensation is explored through simulation calculation and analysis. This study provides theoretical and applied basis for people to better understand the sound sensing mechanism, and provides a numerical simulation platform for further analyzing Corti's sensing mechanism and good clinical application.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Comput Struct Biotechnol J Ano de publicação: 2023 Tipo de documento: Article