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Safety, tolerability, pharmacokinetics, and antiviral activity of the novel core protein allosteric modulator ZM-H1505R (Canocapavir) in chronic hepatitis B patients: a randomized multiple-dose escalation trial.
Jia, Haiyan; Mai, Jiajia; Wu, Min; Chen, Hong; Li, Xiaojiao; Li, Cuiyun; Liu, Jingrui; Liu, Chengjiao; Hu, Yue; Zhu, Xiaoxue; Jiang, Xiuhong; Hua, Bo; Xia, Tian; Liu, Gang; Deng, Aiyun; Liang, Bo; Guo, Ruoling; Lu, Hui; Wang, Zhe; Chen, Huanming; Zhang, Zhijun; Zhang, Hong; Niu, Junqi; Ding, Yanhua.
Afiliação
  • Jia H; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Mai J; Gynecology and Obstetrics Center, the First Hospital of Jilin University, Changchun, China.
  • Wu M; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Chen H; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Li X; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Li C; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Liu J; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Liu C; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Hu Y; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Zhu X; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Jiang X; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China.
  • Hua B; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Xia T; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Liu G; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Deng A; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Liang B; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Guo R; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Lu H; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Wang Z; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Chen H; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Zhang Z; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Zhang H; Shanghai Zhimeng Biopharma, Inc, 1976 Gaoke Middle Road, Suite A-302, Pudong District, Shanghai, China.
  • Niu J; Phase I Clinical Research Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun, Jilin Province, China. zhanghong2015@jlu.edu.cn.
  • Ding Y; Department of Hepatology, Center of Infectious Disease and Pathogen Biology, The First Hospital of Jilin University, Changchun, China. junqiniu@jlu.edu.cn.
BMC Med ; 21(1): 98, 2023 03 16.
Article em En | MEDLINE | ID: mdl-36927420
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Antivirais / Hepatite B Crônica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: BMC Med Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 Base de dados: MEDLINE Assunto principal: Antivirais / Hepatite B Crônica Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Revista: BMC Med Ano de publicação: 2023 Tipo de documento: Article