High-throughput profiling of sequence recognition by tyrosine kinases and SH2 domains using bacterial peptide display.

Li, Allyson; Voleti, Rashmi; Lee, Minhee; Gagoski, Dejan; Shah, Neel H

Li, Allyson; Voleti, Rashmi; Lee, Minhee; Gagoski, Dejan; Shah, Neel H.

Afiliação

Li A; Department of Chemistry, Columbia University, New York, United States.
Voleti R; Department of Chemistry, Columbia University, New York, United States.
Lee M; Department of Chemistry, Columbia University, New York, United States.
Gagoski D; Department of Chemistry, Columbia University, New York, United States.
Shah NH; Department of Biological Sciences, Columbia University, New York, United States.

Elife ; 122023 03 16.

Article em En | MEDLINE | ID: mdl-36927728

Assuntos

Proteínas Tirosina Quinases; Domínios de Homologia de src; Humanos; Proteínas Tirosina Quinases/metabolismo; Fosfotirosina; Fosfopeptídeos/química; Tirosina/metabolismo; Biblioteca de Peptídeos; Fosfotransferases/metabolismo

Palavras-chave

E. coli; amber suppression; biochemistry; cell signaling; chemical biology; deep sequencing; phosphotyrosine; sequence specificity; variant effects

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Domínios de Homologia de src Limite: Humans Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article

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