Comparing the Effectiveness of Phacoemulsification + Endoscopic Cyclophotocoagulation Laser versus Phacoemulsification Alone for the Treatment of Primary Open Angle Glaucoma in Patients with Cataract (CONCEPT): Study Methodology.
Ophthalmol Glaucoma
; 6(5): 474-479, 2023.
Article
em En
| MEDLINE
| ID: mdl-36931429
ABSTRACT
OBJECTIVE:
To describe the methodology of the Comparing the Effectiveness of Phacoemulsification + Endoscopic Cyclophotocoagulation Laser and Phacoemulsification Alone for the Treatment of Primary Open Angle Glaucoma in Patients with Cataract (CONCEPT) study, a randomized controlled trial.DESIGN:
Double-masked, randomized controlled trial. SUBJECTS, PARTICIPANTS, AND/OR CONTROLS Participants will be recruited from 5 United Kingdom-based centers. One hundred and sixty eyes with a diagnosis of primary open-angle glaucoma and visually significant cataract will be included. Eighty eyes will be randomized to undergo cataract surgery alone and eighty to undergo cataract surgery with endoscopic cyclophotocoagulation (ECP).METHODS:
The baseline diurnal washout intraocular pressure (IOP) will be measured. The participants will be randomized to undergo cataract surgery alone or cataract surgery with ECP upon completion of uncomplicated cataract surgery. At the 1- and 2-year post surgery follow-up visits, the measurements of washout diurnal IOP will be repeated. MAIN OUTCOMEMEASURES:
Diurnal washout IOP, use of glaucoma medications, and adverse events.CONCLUSIONS:
We described the methodology of the first randomized controlled trial comparing cataract surgery alone with cataract surgery combined with ECP in the context of patients with primary open-angle glaucoma and symptomatic cataract. FINANCIAL DISCLOSURE(S) Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Catarata
/
Glaucoma
/
Glaucoma de Ângulo Aberto
/
Facoemulsificação
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
Ophthalmol Glaucoma
Ano de publicação:
2023
Tipo de documento:
Article