Schwann cell-specific RhoA knockout accelerates peripheral nerve regeneration via promoting Schwann cell dedifferentiation.

Liu, Jingmin; Ma, Xinrui; Hu, Xiaofang; Wen, Jinkun; Zhang, Haowen; Xu, Jiawei; He, Ye; Wang, Xianghai; Guo, Jiasong

Liu, Jingmin; Ma, Xinrui; Hu, Xiaofang; Wen, Jinkun; Zhang, Haowen; Xu, Jiawei; He, Ye; Wang, Xianghai; Guo, Jiasong.

Afiliação

Liu J; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Ma X; Department of Spine Orthopedics, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China.
Hu X; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Wen J; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Zhang H; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Xu J; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
He Y; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Wang X; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.
Guo J; Department of Histology and Embryology, Guangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China.

Glia ; 71(7): 1715-1728, 2023 07.

Article em En | MEDLINE | ID: mdl-36971019

Assuntos

Traumatismos dos Nervos Periféricos; Neuropatia Ciática; Camundongos; Animais; Desdiferenciação Celular; Nervo Isquiático/metabolismo; Células de Schwann/metabolismo; Neuropatia Ciática/metabolismo; Regeneração Nervosa/fisiologia; Traumatismos dos Nervos Periféricos/metabolismo

Palavras-chave

RhoA; Schwann cells; Wallerian degeneration; dedifferentiation; neurotrophins; peripheral nerve injury

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neuropatia Ciática / Traumatismos dos Nervos Periféricos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Glia Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google