Clinical Presentation of Alpha-Gal Syndrome in Pediatric Gastroenterology and Response to Mammalian Dietary Elimination.
Am J Gastroenterol
; 118(7): 1293-1296, 2023 07 01.
Article
em En
| MEDLINE
| ID: mdl-36995329
ABSTRACT
INTRODUCTION:
Alpha-gal syndrome is an immunoglobulin E (IgE)-mediated delayed hypersensitivity reaction to nonprimate mammalian products, which has a newly established gastrointestinal (GI) phenotype in adults. We assessed the GI presentation and treatment response in children.METHODS:
This is a retrospective study of patients presenting in a pediatric gastroenterology clinic tested for alpha-gal IgE.RESULTS:
Forty of 199 patients (20%) tested had a positive alpha-gal-specific IgE, with 77.5% reporting GI symptoms in isolation. Of the 30 that attempted dietary elimination, 8 (27%) experienced full resolution of symptoms.DISCUSSION:
Alpha-gal syndrome can present with isolated GI symptoms in children.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipersensibilidade Alimentar
/
Gastroenterologia
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Am J Gastroenterol
Ano de publicação:
2023
Tipo de documento:
Article