In silico design and in vivo evaluation of two multi-epitope vaccines containing build-in adjuvant with chitosan nanoparticles against uropathogenic Escherichia coli.

Rezaei, Maryam; Esmaeili, Fariba; Reza Asadi Karam, Mohammad; Ehsani, Parastoo; Abbasnezhad Farsangi, Zeinab; Bouzari, Saeid

Rezaei, Maryam; Esmaeili, Fariba; Reza Asadi Karam, Mohammad; Ehsani, Parastoo; Abbasnezhad Farsangi, Zeinab; Bouzari, Saeid.

Afiliação

Rezaei M; Department of Molecular Biology, Pasteur institute of Iran, Tehran, Iran.
Esmaeili F; Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Reza Asadi Karam M; Department of Molecular Biology, Pasteur institute of Iran, Tehran, Iran.
Ehsani P; Department of Molecular Biology, Pasteur institute of Iran, Tehran, Iran.
Abbasnezhad Farsangi Z; Department of Molecular Biology, Pasteur institute of Iran, Tehran, Iran.
Bouzari S; Department of Molecular Biology, Pasteur institute of Iran, Tehran, Iran. Electronic address: saeidbouzari@yahoo.com.

Int Immunopharmacol ; 117: 109999, 2023 Apr.

Article em En | MEDLINE | ID: mdl-37012877

Assuntos

Quitosana; Nanopartículas; Infecções Urinárias; Escherichia coli Uropatogênica; Vacinas; Animais; Camundongos; Epitopos; Adjuvantes Imunológicos; Infecções Urinárias/prevenção & controle; Imunoglobulina G; Camundongos Endogâmicos BALB C

Palavras-chave

Cellular immune response; Chitosan nano particle (CNP); Humoral immune response; Subunit B of cholera toxin (CTB); Urinary tract infection (UTI)

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 3_ND Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Vacinas / Quitosana / Nanopartículas / Escherichia coli Uropatogênica Limite: Animals Idioma: En Revista: Int Immunopharmacol Ano de publicação: 2023 Tipo de documento: Article

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