FHL2 deficiency impairs follicular development and fertility by attenuating EGF/EGFR/YAP signaling in ovarian granulosa cells.

Wang, Chen; Sun, Hui; Davis, John S; Wang, Xiaojie; Huo, Lijun; Sun, Nan; Huang, Qianzhi; Lv, Xiangmin; Wang, Cheng; He, Chunbo; He, Changjiu; Zhou, Yang; Wu, Jiyun; Yang, Liguo; Hua, Guohua

Wang, Chen; Sun, Hui; Davis, John S; Wang, Xiaojie; Huo, Lijun; Sun, Nan; Huang, Qianzhi; Lv, Xiangmin; Wang, Cheng; He, Chunbo; He, Changjiu; Zhou, Yang; Wu, Jiyun; Yang, Liguo; Hua, Guohua.

Afiliação

Wang C; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Sun H; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Davis JS; Olson Center for Women's Health, Department of Obstetrics & Gynecology, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Wang X; VA Nebraska-Western Iowa Health Care System, Omaha, NE, 68105, USA.
Huo L; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Sun N; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Huang Q; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Lv X; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Wang C; Vincent Center for Reproductive Biology, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
He C; Vincent Center for Reproductive Biology, Vincent Department of Obstetrics and Gynecology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
He C; Olson Center for Women's Health, Department of Obstetrics & Gynecology, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Zhou Y; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Wu J; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Yang L; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.
Hua G; Key Lab of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, Hubei province, 430070, China.

Cell Death Dis ; 14(4): 239, 2023 04 05.

Article em En | MEDLINE | ID: mdl-37015904

Assuntos

Fator de Crescimento Epidérmico; Células da Granulosa; Feminino; Humanos; Camundongos; Animais; Fator de Crescimento Epidérmico/metabolismo; Células da Granulosa/metabolismo; Receptores ErbB/genética; Receptores ErbB/metabolismo; Fator de Transcrição AP-1/metabolismo; Fertilidade; Proteínas Musculares/genética; Proteínas Musculares/metabolismo; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo; Proteínas com Homeodomínio LIM/genética; Proteínas com Homeodomínio LIM/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Epidérmico / Células da Granulosa Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2023 Tipo de documento: Article

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