Clinical gene therapy development for the central nervous system: Candidates and challenges for AAVs.

Leong, Tiffany W; Pal, Arindam; Cai, Qi; Gao, Zhenghong; Li, Xiaoqing; Bleris, Leonidas; Hayenga, Heather N; Qin, Zhenpeng

Leong, Tiffany W; Pal, Arindam; Cai, Qi; Gao, Zhenghong; Li, Xiaoqing; Bleris, Leonidas; Hayenga, Heather N; Qin, Zhenpeng.

Afiliação

Leong TW; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Pal A; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Cai Q; Department of Mechanical Engineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Gao Z; Department of Mechanical Engineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Li X; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Bleris L; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA; Center for Systems Biology, University of Texas at Dallas, Richardson, TX 75080, USA; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX 75080, USA.
Hayenga HN; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA.
Qin Z; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA; Department of Mechanical Engineering, The University of Texas at Dallas, Richardson, TX 75080, USA; Center for Advanced Pain Studies, The University of Texas at Dallas, Richardson, TX 75080, USA; Department o

J Control Release ; 357: 511-530, 2023 05.

Article em En | MEDLINE | ID: mdl-37040842

Assuntos

Doenças do Sistema Nervoso Central; Vetores Genéticos; Humanos; Vetores Genéticos/genética; Sistema Nervoso Central; Terapia Genética/métodos; Doenças do Sistema Nervoso Central/genética; Doenças do Sistema Nervoso Central/terapia

Palavras-chave

Adeno-associated virus; CNS; Gene therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças do Sistema Nervoso Central / Vetores Genéticos Limite: Humans Idioma: En Revista: J Control Release Ano de publicação: 2023 Tipo de documento: Article

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