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Impact of sentinel lymph node assessment on the outcomes of patients with advanced endometrial cancer: A meta-analysis.
Yao, Huiyi; Luo, Ruiwen; Tong, Ruoyi; Wei, Yanwen; Zheng, Kaiteng; Hu, Xiangdan.
Afiliação
  • Yao H; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Luo R; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Tong R; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Wei Y; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Zheng K; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
  • Hu X; Department of Gynecology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Medicine (Baltimore) ; 102(15): e33465, 2023 Apr 14.
Article em En | MEDLINE | ID: mdl-37058063
BACKGROUND: Sentinel lymph node (SLN) assessment is used to treat early endometrial cancer; however, its application in advanced endometrial cancer remains controversial. Therefore, we assessed the effects of SLN assessment and lymphadenectomy (LND) on the prognosis (survival rate and primary outcome) of patients with advanced endometrial cancer. METHODS: Pertinent studies were selected from PubMed, Embase, Web of Science, and the Cochrane Library until March 19, 2022. Relevant studies were strictly screened according to the inclusion and exclusion criteria. Data from the included studies were extracted and their quality was evaluated. Then RevMan5.4 software was used for the meta-analysis. RESULTS: Four retrospective studies were included, which enrolled 7181 patients; 492 were treated with SLN and 6689 with LND. In terms of overall survival, there was no significant difference between the 2 groups (odds ratio = 1.14, 95% confidence interval: 0.92-1.41, I2 = 0%, P = .39). CONCLUSIONS: SLN assessment is an alternative to LND as a treatment modality for advanced endometrial cancer.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Endométrio / Linfonodo Sentinela / Linfadenopatia Tipo de estudo: Observational_studies / Prognostic_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Medicine (Baltimore) Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Endométrio / Linfonodo Sentinela / Linfadenopatia Tipo de estudo: Observational_studies / Prognostic_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Medicine (Baltimore) Ano de publicação: 2023 Tipo de documento: Article