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Delivering the next generation of cancer immunotherapies with RNA.
Raimondo, Theresa M; Reed, Kaelan; Shi, Dennis; Langer, Robert; Anderson, Daniel G.
Afiliação
  • Raimondo TM; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Reed K; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Shi D; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
  • Langer R; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Harvard-Massachusetts Institute of Technology, Division of Health Science and
  • Anderson DG; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Harvard-Massachusetts Institute of Technology, Division of Health Science and
Cell ; 186(8): 1535-1540, 2023 04 13.
Article em En | MEDLINE | ID: mdl-37059063
ABSTRACT
Decades of oncologic clinical use have demonstrated that cancer immunotherapy provides unprecedented therapeutic benefits. Tragically, only a minority of patients respond to existing immunotherapies. RNA lipid nanoparticles have recently emerged as modular tools for immune stimulation. Here, we discuss advancements in RNA-based cancer immunotherapies and opportunities for improvement.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Imunoterapia / Neoplasias Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Imunoterapia / Neoplasias Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2023 Tipo de documento: Article