The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathway.

Zhang, Miao; Bi, Xiaowen; Liu, Shuai; Liu, Yu; Wang, Qiyu

Zhang, Miao; Bi, Xiaowen; Liu, Shuai; Liu, Yu; Wang, Qiyu.

Afiliação

Zhang M; Research Institute of Poyang Lake, Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330096, China.
Bi X; Department of Medical Genetics and Cell Biology, College of Medicine, Nanchang University, Nanchang 330006, China. Electronic address: bixiaowen90@163.com.
Liu S; Research Institute of Poyang Lake, Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330096, China.
Liu Y; Research Institute of Poyang Lake, Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330096, China.
Wang Q; Research Institute of Poyang Lake, Institute of Microbiology, Jiangxi Academy of Sciences, Nanchang 330096, China. Electronic address: ihbwangqiyu@126.com.

Toxicology ; 490: 153511, 2023 05 15.

Article em En | MEDLINE | ID: mdl-37059347

Assuntos

Neoplasias da Retina; Retinoblastoma; Animais; Ratos; Ciclo Celular; Pontos de Checagem do Ciclo Celular; Senescência Celular; Inibidor de Quinase Dependente de Ciclina p21/genética; Inibidor de Quinase Dependente de Ciclina p21/metabolismo; Proteína do Retinoblastoma; Proteína Supressora de Tumor p53/metabolismo

Palavras-chave

Cell cycle arrest; Cell senescence; GH3; OBS; P53

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Retinoblastoma / Neoplasias da Retina Limite: Animals Idioma: En Revista: Toxicology Ano de publicação: 2023 Tipo de documento: Article

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