Molecular Docking and Network Pharmacology Interaction Analysis of Gingko Biloba (EGB761) Extract with Dual Target Inhibitory Mechanism in Alzheimer's Disease.

Singh, Manisha; Jindal, Divya; Kumar, Rupesh; Pancham, Pranav; Haider, Shazia; Gupta, Vivek; Mani, Shalini; R, Rachana; Tiwari, Raj Kumar; Chanda, Silpi

Singh, Manisha; Jindal, Divya; Kumar, Rupesh; Pancham, Pranav; Haider, Shazia; Gupta, Vivek; Mani, Shalini; R, Rachana; Tiwari, Raj Kumar; Chanda, Silpi.

Afiliação

Singh M; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Jindal D; Flinders Health and Medical Research Institute, College of Medicine & Public Health, Flinders University, Adelaide, Australia.
Kumar R; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Pancham P; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Haider S; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Gupta V; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Mani S; Macquarie Medical School, Macquarie University, Sydney, Australia.
R R; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Tiwari RK; Department of Biotechnology, Jaypee Institute of Information Technology (JIIT), Noida, India.
Chanda S; Department of Pharmacognosy, Era College of Pharmacy, Era University, Lucknow, Uttar Pradesh, India.

J Alzheimers Dis ; 93(2): 705-726, 2023.

Article em En | MEDLINE | ID: mdl-37066913

Assuntos

Doença de Alzheimer; Ginkgo biloba; Humanos; Idoso; Ginkgo biloba/metabolismo; Doença de Alzheimer/tratamento farmacológico; Doença de Alzheimer/metabolismo; Simulação de Acoplamento Molecular; Glicogênio Sintase Quinase 3 beta; Quempferóis/farmacologia; Quempferóis/uso terapêutico; Quercetina/uso terapêutico; Acetilcolinesterase/metabolismo; Farmacologia em Rede; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico

Palavras-chave

Acetylcholinesterase inhibitors; amyloid-ß; compound target network; neurodegenerative disorders; neurofibrillary tangles; phytocompounds

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ginkgo biloba / Doença de Alzheimer Tipo de estudo: Risk_factors_studies / Screening_studies Limite: Aged / Humans Idioma: En Revista: J Alzheimers Dis Ano de publicação: 2023 Tipo de documento: Article

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