I2-Mediated [6 + 1] Annulation of Alkynes with MsONH3OTf: Direct Synthesis of Benzo[b]azepines.
Org Lett
; 25(17): 3007-3012, 2023 May 05.
Article
em En
| MEDLINE
| ID: mdl-37083284
The synthesis of benzo[b]azepines using protonated aminating reagent (MsONH3OTf) and alkynes through I2-mediated [6 + 1] annulation reaction has been developed. This protocol features excellent functional group tolerance and mild reaction conditions and affords the benzo[b]azepines in moderate to good yields under metal-free reaction conditions.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Revista:
Org Lett
Ano de publicação:
2023
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Article