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Complex PK-PD of an engineered IL-15/IL-15Rα-Fc fusion protein in cynomolgus monkeys: QSP modeling of lymphocyte dynamics.
Lu, Dan; Yadav, Rajbharan; Holder, Patrick; Chiang, Eugene; Sanjabi, Shomyseh; Poon, Victor; Bernett, Matthew; Varma, Rajat; Liu, Ke; Leung, Irene; Bogaert, Liz; Desjarlais, John; Shivva, Vittal; Hosseini, Iraj; Ramanujan, Saroja.
Afiliação
  • Lu D; Genentech, Inc., South San Francisco, CA 94080, United States. Electronic address: lu.dan@gene.com.
  • Yadav R; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Holder P; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Chiang E; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Sanjabi S; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Poon V; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Bernett M; Xencor, Inc. Monrovia, CA 94080, United States.
  • Varma R; Xencor, Inc. Monrovia, CA 94080, United States.
  • Liu K; Xencor, Inc. Monrovia, CA 94080, United States.
  • Leung I; Xencor, Inc. Monrovia, CA 94080, United States.
  • Bogaert L; Xencor, Inc. Monrovia, CA 94080, United States.
  • Desjarlais J; Xencor, Inc. Monrovia, CA 94080, United States.
  • Shivva V; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Hosseini I; Genentech, Inc., South San Francisco, CA 94080, United States.
  • Ramanujan S; Genentech, Inc., South San Francisco, CA 94080, United States. Electronic address: ramanujan.saroja@gene.com.
Eur J Pharm Sci ; 186: 106450, 2023 Jul 01.
Article em En | MEDLINE | ID: mdl-37084985
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-15 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Pharm Sci Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-15 / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Eur J Pharm Sci Ano de publicação: 2023 Tipo de documento: Article