New triazole-attached quinoxalines selectively recognize the telomeric multimeric G-quadruplexes and inhibit breast cancer cell growth.

Hu, Ming-Hao; Lin, Jia-Hong

Hu, Ming-Hao; Lin, Jia-Hong.

Afiliação

Hu MH; Nation-Regional Engineering Lab for Synthetic Biology of Medicine, International Cancer Center, School of Pharmacy, Shenzhen University Medical School, Shenzhen 518060, China; Shenzhen Key Laboratory for Nano-Biosensing Technology (ZDSYS20210112161400001), Shenzhen University Medical School, Shenzhen 518060, China. Electronic address: humhao1229@szu.edu.cn.
Lin JH; Nation-Regional Engineering Lab for Synthetic Biology of Medicine, International Cancer Center, School of Pharmacy, Shenzhen University Medical School, Shenzhen 518060, China.

Int J Biol Macromol ; 241: 124548, 2023 Jun 30.

Article em En | MEDLINE | ID: mdl-37094649

Assuntos

Antineoplásicos; Neoplasias da Mama; Quadruplex G; Humanos; Feminino; Quinoxalinas/farmacologia; Neoplasias da Mama/tratamento farmacológico; Antineoplásicos/farmacologia; Antineoplásicos/química; Telômero; Ligantes

Palavras-chave

Breast cancer; Multimeric G-quadruplex; Selective; Telomere; Triazole

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Quadruplex G / Antineoplásicos Limite: Female / Humans Idioma: En Revista: Int J Biol Macromol Ano de publicação: 2023 Tipo de documento: Article

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