Treating Neurogenic Lower Urinary Tract Dysfunction in Chronic Spinal Cord Injury Patients-When Intravesical Botox Injection or Urethral Botox Injection Are Indicated.
Toxins (Basel)
; 15(4)2023 04 17.
Article
em En
| MEDLINE
| ID: mdl-37104226
ABSTRACT
Lower urinary tract symptoms (LUTS), such as urgency, urinary incontinence, and/or difficulty voiding, hamper the quality of life (QoL) of patients with spinal cord injury (SCI). If not managed adequately, urological complications, such as urinary tract infection or renal function deterioration, may further deteriorate the patient's QoL. Botulinum toxin A (BoNT-A) injection within the detrusor muscle or urethral sphincter yields satisfactory therapeutic effects for treating urinary incontinence or facilitating efficient voiding; however, adverse effects inevitably follow its therapeutic efficacy. It is important to weigh the merits and demerits of BoNT-A injection for LUTS and provide an optimal management strategy for SCI patients. This paper summarizes different aspects of the application of BoNT-A injection for lower urinary tract dysfunctions in SCI patients and provides an overview of the benefits and drawbacks of this treatment.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traumatismos da Medula Espinal
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Incontinência Urinária
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Bexiga Urinaria Neurogênica
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Toxinas Botulínicas Tipo A
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Fármacos Neuromusculares
Tipo de estudo:
Etiology_studies
Aspecto:
Patient_preference
Limite:
Humans
Idioma:
En
Revista:
Toxins (Basel)
Ano de publicação:
2023
Tipo de documento:
Article