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The significance of quercetin-loaded advanced nanoformulations for the management of diabetic wounds.
Panthi, Vijay Kumar; Imran, Mohammad; Chaudhary, Arshi; Paudel, Keshav Raj; Mohammed, Yousuf.
Afiliação
  • Panthi VK; Department of Pharmacy, College of Pharmacy & Natural Medicine Research Institute, Mokpo National University, Muan-gun, Jeonnam, 58554, Republic of Korea.
  • Imran M; Therapeutic Research Group, Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, 4102, Australia.
  • Chaudhary A; Department of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi, 110062, India.
  • Paudel KR; Department of Oriental Medicine Resources, Mokpo National University, Muan-gun, Jeonnam, 58554, Republic of Korea.
  • Mohammed Y; Therapeutic Research Group, Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, 4102, Australia.
Nanomedicine (Lond) ; 18(4): 391-411, 2023 02.
Article em En | MEDLINE | ID: mdl-37140389
Quercetin is a well-known plant flavanol that exhibits multiple biological activities, including antioxidant, anti-inflammatory and anticancer activities. The role of quercetin in wound healing has been widely explored by a range of researchers in different models. However, the physicochemical properties, such as solubility and permeability, of this compound are low, which ultimately limits its bioavailability on the target site. To overcome these limitations for successful therapy, scientists have developed a range of nanoformulations that provide effective therapeutic potential. In this review, the broad mechanism of quercetin for acute and chronic wounds is covered. A compilation of recent advances on the horizon of wound healing via quercetin is incorporated with several advanced nanoformulations.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quercetina / Diabetes Mellitus Limite: Humans Idioma: En Revista: Nanomedicine (Lond) Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quercetina / Diabetes Mellitus Limite: Humans Idioma: En Revista: Nanomedicine (Lond) Ano de publicação: 2023 Tipo de documento: Article