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Efficient prime editing in mouse brain, liver and heart with dual AAVs.
Davis, Jessie R; Banskota, Samagya; Levy, Jonathan M; Newby, Gregory A; Wang, Xiao; Anzalone, Andrew V; Nelson, Andrew T; Chen, Peter J; Hennes, Andrew D; An, Meirui; Roh, Heejin; Randolph, Peyton B; Musunuru, Kiran; Liu, David R.
Afiliação
  • Davis JR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Banskota S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Levy JM; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Newby GA; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Wang X; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Anzalone AV; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Nelson AT; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Chen PJ; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Hennes AD; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • An M; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Roh H; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Randolph PB; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, USA.
  • Musunuru K; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
  • Liu DR; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Nat Biotechnol ; 42(2): 253-264, 2024 Feb.
Article em En | MEDLINE | ID: mdl-37142705
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edição de Genes / RNA Guia de Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: Nat Biotechnol Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edição de Genes / RNA Guia de Sistemas CRISPR-Cas Limite: Animals Idioma: En Revista: Nat Biotechnol Ano de publicação: 2024 Tipo de documento: Article