Capsular polysaccharide inhibits vaccine-induced O-antigen antibody binding and function across both classical and hypervirulent K2:O1 strains of Klebsiella pneumoniae.

Wantuch, Paeton L; Knoot, Cory J; Robinson, Lloyd S; Vinogradov, Evgeny; Scott, Nichollas E; Harding, Christian M; Rosen, David A

Wantuch, Paeton L; Knoot, Cory J; Robinson, Lloyd S; Vinogradov, Evgeny; Scott, Nichollas E; Harding, Christian M; Rosen, David A.

Afiliação

Wantuch PL; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, United States of America.
Knoot CJ; Omniose, Saint Louis, Missouri, United States of America.
Robinson LS; Omniose, Saint Louis, Missouri, United States of America.
Vinogradov E; National Research Council Canada, Human Health Therapeutics Centre, Ottawa, Ontario, Canada.
Scott NE; Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia.
Harding CM; Omniose, Saint Louis, Missouri, United States of America.
Rosen DA; Department of Pediatrics, Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

PLoS Pathog ; 19(5): e1011367, 2023 05.

Article em En | MEDLINE | ID: mdl-37146068

Assuntos

Infecções por Klebsiella; Vacinas; Camundongos; Animais; Virulência; Antígenos O; Klebsiella pneumoniae; Lipopolissacarídeos/metabolismo; Antibacterianos/farmacologia; Infecções por Klebsiella/prevenção & controle

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Vacinas Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: PLoS Pathog Ano de publicação: 2023 Tipo de documento: Article

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