Eucommiae cortex polysaccharides attenuate gut microbiota dysbiosis and neuroinflammation in mice exposed to chronic unpredictable mild stress: Beneficial in ameliorating depressive-like behaviors.

Wang, Mengli; Sun, Penghao; Li, Zhuoni; Li, Jing; Lv, Xin; Chen, Shulin; Zhu, Xiaoyan; Chai, Xuejun; Zhao, Shanting

Wang, Mengli; Sun, Penghao; Li, Zhuoni; Li, Jing; Lv, Xin; Chen, Shulin; Zhu, Xiaoyan; Chai, Xuejun; Zhao, Shanting.

Afiliação

Wang M; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Sun P; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Li Z; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Li J; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Lv X; College of Food Science and Engineering, Northwest A&F University, Yangling, China.
Chen S; College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Zhu X; College of Veterinary Medicine, Northwest A&F University, Yangling, China. Electronic address: xyzhu0922@nwsuaf.edu.cn.
Chai X; College of Basic Medicine, Xi'an Medical University, Xi'an, China. Electronic address: xchai@xiyi.edu.cn.
Zhao S; College of Veterinary Medicine, Northwest A&F University, Yangling, China. Electronic address: zhaoshanting@nwsuaf.edu.cn.

J Affect Disord ; 334: 278-292, 2023 08 01.

Article em En | MEDLINE | ID: mdl-37156274

Assuntos

Depressão; Microbioma Gastrointestinal; Camundongos; Masculino; Animais; Depressão/etiologia; Doenças Neuroinflamatórias; Disbiose/tratamento farmacológico; Disbiose/metabolismo; Polissacarídeos/farmacologia; Polissacarídeos/uso terapêutico; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Hipocampo/metabolismo; Lipopolissacarídeos/farmacologia; Estresse Psicológico/complicações; Estresse Psicológico/tratamento farmacológico; Modelos Animais de Doenças

Palavras-chave

Adult neurogenesis; Chronic unpredictable mild stress; Eucommiae cortex polysaccharides; Gut microbiota; Neuroinflammation

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND Base de dados: MEDLINE Assunto principal: Depressão / Microbioma Gastrointestinal Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals Idioma: En Revista: J Affect Disord Ano de publicação: 2023 Tipo de documento: Article

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