Tegument proteins of Epstein-Barr virus: Diverse functions, complex networks, and oncogenesis.
Tumour Virus Res
; 15: 200260, 2023 06.
Article
em En
| MEDLINE
| ID: mdl-37169175
The tegument is the structure between the envelope and nucleocapsid of herpesvirus particles. Viral (and cellular) proteins accumulate to create the layers of the tegument. Some Epstein-Barr virus (EBV) tegument proteins are conserved widely in Herpesviridae, but others are shared only by members of the gamma-herpesvirus subfamily. As the interface to envelope and nucleocapsid, the tegument functions in virion morphogenesis and budding of the nucleocapsid during progeny production. When a virus particle enters a cell, enzymes such as kinase and deubiquitinase, and transcriptional activators are released from the virion to promote virus infection. Moreover, some EBV tegument proteins are involved in oncogenesis. Here, we summarize the roles of EBV tegument proteins, in comparison to those of other herpesviruses.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Vírus Epstein-Barr
/
Herpesviridae
Limite:
Humans
Idioma:
En
Revista:
Tumour Virus Res
Ano de publicação:
2023
Tipo de documento:
Article