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Discovery of myrsinane-type Euphorbia diterpene derivatives through a skeleton conversion strategy from lathyrane diterpene for the treatment of Alzheimer's disease.
Xiao, Yao; Zhang, Yang; Ji, Wan-Sheng; Jia, Xiao-Nan; Shan, Lian-Hai; Li, Xiaohuan; Liu, Yan-Jun; Jiang, Ting; Gao, Feng.
Afiliação
  • Xiao Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Zhang Y; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Ji WS; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Jia XN; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Shan LH; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Li X; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China.
  • Liu YJ; The Center of Gastrointestinal and Minimally Invasive Surgery, Department of General Surgery, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, Chengdu 610031, PR China. Electronic address: liuyanjun_001@163.com.
  • Jiang T; Department of Pharmacy, The First Afflicted Hospital of Chengdu Medical College, Chengdu 610500, PR China. Electronic address: jiangtingtina@163.com.
  • Gao F; Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, PR China. Electronic address: gaof@swjtu.edu.cn.
Bioorg Chem ; 138: 106595, 2023 09.
Article em En | MEDLINE | ID: mdl-37178652
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Euphorbia / Diterpenos / Doença de Alzheimer / Neuroblastoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fármacos Neuroprotetores / Euphorbia / Diterpenos / Doença de Alzheimer / Neuroblastoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article