Epigenomic profiling of isolated blood cell types reveals highly specific B cell smoking signatures and links to disease risk.

Wang, Xuting; Campbell, Michelle R; Cho, Hye-Youn; Pittman, Gary S; Martos, Suzanne N; Bell, Douglas A

Wang, Xuting; Campbell, Michelle R; Cho, Hye-Youn; Pittman, Gary S; Martos, Suzanne N; Bell, Douglas A.

Afiliação

Wang X; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA. wang21@niehs.nih.gov.
Campbell MR; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
Cho HY; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
Pittman GS; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
Martos SN; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA.
Bell DA; Environmental Epigenomics and Disease Group, Immunity, Inflammation and Disease Laboratory, Intramural Research Program, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, 27709, USA. bell1@niehs.nih.gov.

Clin Epigenetics ; 15(1): 90, 2023 05 25.

Article em En | MEDLINE | ID: mdl-37231515

Assuntos

Metilação de DNA; Fumar; Adulto; Humanos; Fumar/efeitos adversos; Fumar/genética; Estudo de Associação Genômica Ampla; Epigenômica; Leucócitos; Fumar Tabaco; Ilhas de CpG; Epigênese Genética

Palavras-chave

Blood cell types; DNA methylation; Epigenome-wide association study; Genetic variation; Memory B cell; Tobacco smoking

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fumar / Metilação de DNA Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Adult / Humans Idioma: En Revista: Clin Epigenetics Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google