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Inhibition of FGF23 is a therapeutic strategy to target hematopoietic stem cell niche defects in ß-thalassemia.
Aprile, Annamaria; Raggi, Laura; Bolamperti, Simona; Villa, Isabella; Storto, Mariangela; Morello, Gaia; Marktel, Sarah; Tripodo, Claudio; Cappellini, Maria Domenica; Motta, Irene; Rubinacci, Alessandro; Ferrari, Giuliana.
Afiliação
  • Aprile A; San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Raggi L; San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Bolamperti S; University of Milano Bicocca, 20126 Milan, Italy.
  • Villa I; Bone Metabolism Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Storto M; Endocrine and Osteometabolic Laboratory, Institute of Endocrine and Metabolic Sciences, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Morello G; Bone Metabolism Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Marktel S; Endocrine and Osteometabolic Laboratory, Institute of Endocrine and Metabolic Sciences, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Tripodo C; San Raffaele-Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Cappellini MD; Tumor Immunology Unit, Human Pathology Section, Department of Health Sciences, University of Palermo, 90134 Palermo, Italy.
  • Motta I; Hematology and Bone Marrow Transplantation Unit, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
  • Rubinacci A; Tumor Immunology Unit, Human Pathology Section, Department of Health Sciences, University of Palermo, 90134 Palermo, Italy.
  • Ferrari G; IFOM ETS, AIRC Institute of Molecular Oncology, 20139 Milan, Italy.
Sci Transl Med ; 15(698): eabq3679, 2023 05 31.
Article em En | MEDLINE | ID: mdl-37256933
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Talassemia beta / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Talassemia beta / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Transl Med Ano de publicação: 2023 Tipo de documento: Article