Modulation of Thalamocingulate Nociceptive Transmission and Glutamate Secretion by Targeting P2×7 Receptor.

Kuan, Yung-Hui; Li, Fu-An; Cheng, Sin-Jhong; Chang, Wei-Peng; Shyu, Bai-Chuang

Kuan, Yung-Hui; Li, Fu-An; Cheng, Sin-Jhong; Chang, Wei-Peng; Shyu, Bai-Chuang.

Afiliação

Kuan YH; Division of Neuroscience, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Li FA; Proteomics Core Facility, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Cheng SJ; Neuro Circuit Electrophysiology Core Facility, Neuroscience Program, Academia Sinica (NPAS), Taipei, Taiwan.
Chang WP; Department of Organismal Biology & Anatomy, University of Chicago, Chicago, Illinois.
Shyu BC; Division of Neuroscience, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan. Electronic address: bmbai@gate.sinica.edu.tw.

J Pain ; 24(11): 1915-1930, 2023 11.

Article em En | MEDLINE | ID: mdl-37271352

Assuntos

Nociceptividade; Dor; Humanos; Dor/metabolismo; Neurônios/metabolismo; Glutamatos/metabolismo; Glutamatos/farmacologia; Trifosfato de Adenosina/metabolismo; Trifosfato de Adenosina/farmacologia; Receptores Purinérgicos P2X7/metabolismo

Palavras-chave

P2×7; adenosine triphosphate; glutamate; pain; thalamocingulate circuit

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Nociceptividade Limite: Humans Idioma: En Revista: J Pain Ano de publicação: 2023 Tipo de documento: Article

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