"How sad it is! I shall grow old, and horrible, and dreadful" - The ups and downs of cell senescence.

ABSTRACT

This issue of the Biomedical Journal contains a special section about cell senescence. The reader gets an insight into the crosstalk between immune system and senescent cells, into an approach to fight aging by tweaking macronutrient intake, and also learns about the connection that does (not) exist between body mass and cancer risk. Further articles in the current issue give details about the effect of Damask rose on PCOS, illustrate the issues gender bias may exert in research studies, go into a joint drug approach in ischemia-reperfusion injury, and a promising tool to diagnose Parkinsonian disorders. Two articles dive into challenges related to obstructive sleep apnea, another article explores the benefits a composite mixture may have for improving bone cement material, with lastly a research team presenting a modified procedure to managing involutional lower eyelid entropion in individuals of Asian descent. Finally, BMJ issue 46-3 is complemented with a correspondence about mpox spreading from endemic areas to other parts of the world.