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Joint distraction using a purpose-built device for knee osteoarthritis: a prospective 2-year follow-up.
Struik, Thijmen; Mastbergen, Simon C; Brouwer, Reinoud W; Custers, Roel J H; van Geenen, Rutger C I; Heusdens, Christiaan H W; Emans, Pieter J; Huizinga, Maarten R; Jansen, Mylène P.
Afiliação
  • Struik T; Department of Rheumatology & Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Mastbergen SC; Department of Rheumatology & Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • Brouwer RW; Department of Orthopedics, Martini Hospital, Groningen, The Netherlands.
  • Custers RJH; Department of Orthopedic Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands.
  • van Geenen RCI; Department of Orthopedics, Amphia Hospital, Breda, The Netherlands.
  • Heusdens CHW; Department of Orthopedics, University Hospital Antwerp, Edegem, Antwerp, Belgium.
  • Emans PJ; Antwerp Surgical Training, Anatomy and Research Centre (ASTARC), Faculty of Medicine and Health Sciences, University of Antwerp, Wilrijk, Belgium.
  • Huizinga MR; Department of Orthopedics, Joint-Preserving Clinic, Maastricht University Medical Centre+, Maastricht, The Netherlands.
  • Jansen MP; Department of Orthopedics, Martini Hospital, Groningen, The Netherlands.
RMD Open ; 9(2)2023 06.
Article em En | MEDLINE | ID: mdl-37290929
OBJECTIVE: Knee distraction treatment for end-stage osteoarthritis successfully postpones arthroplasty for years. Studies performed thus far used general intended use, patient-personalised or custom-made devices. In this study, for the first time, a device specifically designed for knee distraction is evaluated. DESIGN: 65 patients (≤65 years) with end-stage knee osteoarthritis indicated for arthroplasty received knee distraction. Before, 1-year and 2-year post-treatment, questionnaires were filled out and knee radiographs made. Adverse events and self-reported pain medication were registered. RESULTS: Forty-nine patients completed 2-year follow-up: one patient did not complete treatment, three patients received arthroplasty in the first and four patients in the second year follow-up. Eight patients were lost to follow-up in the second year. The total Western Ontario and McMaster Universities Osteoarthritis Index score showed a clinically relevant improvement at 1 and 2 years (+26 and +24 points), as did all subscales (all p<0.001). The minimum radiographic joint space width improved over 1 (+0.5 mm; p<0.001) and 2 (+0.4 mm; p=0.015) years, as did the physical Short-Form 36 (+10 points; p<0.001). The most common adverse event was pin tract infection, experienced by 66% of patients, in 88% successfully treated with oral antibiotics. In two cases, hospitalisation and/or intravenous antibiotics were needed. Eight patients experienced device-related complications. None of the complications influenced 2-year outcomes. Before treatment, 42% of patients used pain medication, which had nearly been halved 1 (23%; p=0.02) and 2 years (29%; p=0.27) post-treatment. CONCLUSIONS: Patients treated with a general applicable, for knee distraction purpose-built device showed, despite adverse events, significant clinical and structural improvement over 2 years. TRIAL REGISTRATION NUMBER: NL7986.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: RMD Open Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite do Joelho Tipo de estudo: Observational_studies / Prognostic_studies Limite: Humans Idioma: En Revista: RMD Open Ano de publicação: 2023 Tipo de documento: Article