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Memory deficits in a juvenile rat model of type 1 diabetes are due to excess 11ß-HSD1 activity, which is upregulated by high glucose concentrations rather than insulin deficiency.
Brossaud, Julie; Bosch-Bouju, Clémentine; Marissal-Arvy, Nathalie; Campas-Lebecque, Marie-Neige; Helbling, Jean-Christophe; Webster, Scott P; Walker, Brian R; Fioramonti, Xavier; Ferreira, Guillaume; Barat, Pascal; Corcuff, Jean-Benoît; Moisan, Marie-Pierre.
Afiliação
  • Brossaud J; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France. julie.brossaud@chu-bordeaux.fr.
  • Bosch-Bouju C; CHU Bordeaux, Nuclear Medicine, Pessac, France. julie.brossaud@chu-bordeaux.fr.
  • Marissal-Arvy N; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Campas-Lebecque MN; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Helbling JC; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Webster SP; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Walker BR; British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Fioramonti X; British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
  • Ferreira G; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Barat P; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Corcuff JB; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
  • Moisan MP; University of Bordeaux, INRAE, Bordeaux INP, NutriNeurO, UMR 1286, Bordeaux, France.
Diabetologia ; 66(9): 1735-1747, 2023 09.
Article em En | MEDLINE | ID: mdl-37300580
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 1 Limite: Animals Idioma: En Revista: Diabetologia Ano de publicação: 2023 Tipo de documento: Article