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An exploration on retro-construction of plasma drug concentration-time curves from corresponding urine excretion data and single-point plasma concentrations using a simplified and idealized method.
Li, Guanglu; Zhang, Wenpeng; Zhang, Meng; Xu, Jiamin; Zhu, Guanghua; Li, Jinglai; Luo, Huan; Zhuang, Xiaomei; Wang, Quanjun; Zhang, Tianhong.
Afiliação
  • Li G; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
  • Zhang W; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
  • Zhang M; Department of Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
  • Xu J; Department of Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
  • Zhu G; Department of Clinical Research Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
  • Li J; Guoke Excellence (Beijing) Medicine Technology Research Co., Ltd., Beijing, China.
  • Luo H; Guoke Excellence (Beijing) Medicine Technology Research Co., Ltd., Beijing, China.
  • Zhuang X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
  • Wang Q; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
  • Zhang T; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Transl Pediatr ; 12(5): 845-860, 2023 May 30.
Article em En | MEDLINE | ID: mdl-37305729
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Aspecto: Ethics Idioma: En Revista: Transl Pediatr Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Aspecto: Ethics Idioma: En Revista: Transl Pediatr Ano de publicação: 2023 Tipo de documento: Article