Glucocorticoid-induced activation of NOX/ROS/NF-&#954;B signaling in MSCs contributes to the development of GONFH.

Xu, Huihui; Zeng, Qinghe; Zou, Kaiao; Huang, Haipeng; Chen, Jiali; Wang, Pinger; Yuan, Wenhua; Xiao, Luwei; Tong, Peijian; Jin, Hongting

Glucocorticoid-induced activation of NOX/ROS/NF-κB signaling in MSCs contributes to the development of GONFH.

Xu, Huihui; Zeng, Qinghe; Zou, Kaiao; Huang, Haipeng; Chen, Jiali; Wang, Pinger; Yuan, Wenhua; Xiao, Luwei; Tong, Peijian; Jin, Hongting.

Afiliação

Xu H; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, China.
Zeng Q; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Zou K; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang, 310053, China.
Huang H; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, China.
Chen J; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Wang P; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang, 310053, China.
Yuan W; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, China.
Xiao L; The First College of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310053, China.
Tong P; Institute of Orthopaedics and Traumatology of Zhejiang Province, Hangzhou, Zhejiang, 310053, China.
Jin H; The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, China.

Apoptosis ; 28(9-10): 1332-1345, 2023 10.

Article em En | MEDLINE | ID: mdl-37306805

Assuntos

Células-Tronco Mesenquimais; NF-kappa B; Humanos; Ratos; Animais; NF-kappa B/genética; NF-kappa B/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Glucocorticoides/efeitos adversos; Glucocorticoides/metabolismo; Apoptose; Transdução de Sinais

Palavras-chave

Apoptosis; Differentiation; GONFH; Mesenchymal stem cell; Oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: NF-kappa B / Células-Tronco Mesenquimais Limite: Animals / Humans Idioma: En Revista: Apoptosis Ano de publicação: 2023 Tipo de documento: Article

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