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A physical tug-of-war and the evolution of immune cells.
Tiwari, Akshay; Dixit, Narendra M.
Afiliação
  • Tiwari A; Department of Chemical Engineering, Indian Institute of Science.
J Biosci ; 482023.
Article em En | MEDLINE | ID: mdl-37337647
Antibodies form an important component of our immune response to pathogens. A robust antibody response can lead to the swift clearance of infection. The protection offered by COVID-19 vaccines has been attributed in large measure to the antibodies they elicit (Padmanabhan et al. 2022). Yet, with other pathogens like HIV-1, vaccines that elicit potent antibodies have remained elusive despite intense efforts over decades (Burton 2019). It is important, therefore, to understand how our body mounts a robust antibody response specific to an invading pathogen or vaccine. A remarkable manifestation of Darwinian evolution happens to be at the heart of such a response.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Revista: J Biosci Ano de publicação: 2023 Tipo de documento: Article
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas contra COVID-19 / COVID-19 Limite: Humans Idioma: En Revista: J Biosci Ano de publicação: 2023 Tipo de documento: Article