Simultaneous determination of enantiomeric and organic impurities of vildagliptin on a cellulose tris(3-chloro-4-methylphenylcarbamate) column under revered-phase conditions.

Papp, Lajos-Attila; Hancu, Gabriel; Szabó, Zoltán-István

Papp, Lajos-Attila; Hancu, Gabriel; Szabó, Zoltán-István.

Afiliação

Papp LA; Department of Pharmaceutical and Therapeutic Chemistry, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu MureÈ, 540142 Târgu MureÈ, Romania.
Hancu G; Department of Pharmaceutical and Therapeutic Chemistry, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu MureÈ, 540142 Târgu MureÈ, Romania. Electronic address: gabriel.hancu@umfst.ro.
Szabó ZI; Department of Drugs Industry and Pharmaceutical Management, Faculty of Pharmacy, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Târgu MureÈ, 540142 Târgu MureÈ, Romania.

J Pharm Biomed Anal ; 234: 115495, 2023 Sep 20.

Article em En | MEDLINE | ID: mdl-37343452

Assuntos

Amilose; Metanol; Vildagliptina; Celulose; Cromatografia Líquida de Alta Pressão/métodos; Água; Estereoisomerismo

Palavras-chave

Enantiomeric impurity; High performance liquid chromatography; Polysaccharide based chiral column; Simultaneous chiral-achiral separation; Structurally related impurities; Vildagliptin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metanol / Amilose Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google