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A sensitive and rapid LC-MS/MS assay for quantitation of free payload Aur0101 from antibody drug conjugate (ADC) PYX-201 in human plasma.
Yin, Feng; Adhikari, Diana; Li, Yan; Turner, Devan; Shane Woolf, M; Lebarbenchon, Diane; Ma, Eric; Mylott, William; Shaheen, Elizabeth; Harriman, Shawn; Pinkas, Jan.
Afiliação
  • Yin F; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Adhikari D; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Li Y; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Turner D; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Shane Woolf M; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Lebarbenchon D; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Ma E; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Mylott W; Chromatographic Services - Research & Development, Biologics by LC-MS/MS, PPD Laboratory Services (a part of ThermoFisher Scientific), 8700 Quioccasin Road, Henrico, VA 23229, USA.
  • Shaheen E; Department of Project Management, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Harriman S; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA.
  • Pinkas J; Department of Nonclinical Research, Pyxis Oncology, Inc., 321 Harrison Avenue, Suite 1, Boston, MA 02118, USA. Electronic address: sharriman@pyxisoncology.com.
J Chromatogr B Analyt Technol Biomed Life Sci ; 1226: 123786, 2023 Jul 15.
Article em En | MEDLINE | ID: mdl-37352642
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Espectrometria de Massas em Tandem Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2023 Tipo de documento: Article