Multi-organ metastases of primary chondrosarcoma of the mammary gland of a spayed Toy Poodle.
J Comp Pathol
; 204: 35-38, 2023 Jul.
Article
em En
| MEDLINE
| ID: mdl-37352824
ABSTRACT
We report the clinical and histopathological findings associated with multi-organ metastases of primary mammary chondrosarcoma in a 12-year-old spayed female Toy Poodle. At post-mortem examination, multifocal, sharply demarcated, grey-white to bright brown, round nodules of variable size were randomly distributed in the lungs, myocardium, liver, pancreas, spleen, intestinal tract and kidneys. Histologically, immature cartilage structures and primitive mesenchymal cells were seen in these organs. Neoplastic cells located in the cartilaginous basophilic extracellular matrix had cytoplasmic vacuolation and round vesicular nuclei and were stained with Safranin O and Alcian blue. To the best of our knowledge, this is the first report of a multi-organ metastatic chondrosarcoma that originated in the mammary gland of a dog.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Ósseas
/
Condrossarcoma
/
Doenças do Cão
Limite:
Animals
Idioma:
En
Revista:
J Comp Pathol
Ano de publicação:
2023
Tipo de documento:
Article