Treatment of osteoporosis using a selective androgen receptor modulator ostarine in an orchiectomized rat model.

Böker, K O; Komrakova, M; Fahrendorff, L; Spelsberg, B R; Hoffmann, D B; Schilling, A F; Lehmann, W; Taudien, S; Sehmisch, S

Böker, K O; Komrakova, M; Fahrendorff, L; Spelsberg, B R; Hoffmann, D B; Schilling, A F; Lehmann, W; Taudien, S; Sehmisch, S.

Afiliação

Böker KO; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany. kai.boeker@med.uni-goettingen.de.
Komrakova M; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Fahrendorff L; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Spelsberg BR; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Hoffmann DB; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Schilling AF; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Lehmann W; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.
Taudien S; Division of Infection Control and Infectious Diseases, University Medical Center Goettingen, 37075, Goettingen, Germany.
Sehmisch S; Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Goettingen, Goettingen, Germany.

Endocrine ; 81(3): 579-591, 2023 09.

Article em En | MEDLINE | ID: mdl-37378829

Assuntos

Osteoporose; Receptores Androgênicos; Ratos; Masculino; Animais; Ratos Sprague-Dawley; Densidade Óssea/fisiologia; Osteoporose/tratamento farmacológico; Osteoporose/prevenção & controle; Androgênios/farmacologia; Androgênios/uso terapêutico; Testosterona/farmacologia; Testosterona/uso terapêutico; Antagonistas de Androgênios/uso terapêutico; Orquiectomia

Palavras-chave

Orchiectomized (Orx) rat model; Ostarine; Osteoporosis; Selective androgen receptor modulator (SARM)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoporose / Receptores Androgênicos Limite: Animals Idioma: En Revista: Endocrine Ano de publicação: 2023 Tipo de documento: Article

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