DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition.

Mishima, Eikan; Nakamura, Toshitaka; Zheng, Jiashuo; Zhang, Weijia; Mourão, André Santos Dias; Sennhenn, Peter; Conrad, Marcus

Mishima, Eikan; Nakamura, Toshitaka; Zheng, Jiashuo; Zhang, Weijia; Mourão, André Santos Dias; Sennhenn, Peter; Conrad, Marcus.

Afiliação

Mishima E; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Nakamura T; Division of Nephrology, Rheumatology and Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Zheng J; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Zhang W; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Mourão ASD; Institute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Sennhenn P; Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Conrad M; transMedChem, Munich, Germany.

Nature ; 619(7968): E9-E18, 2023 Jul.

Article em En | MEDLINE | ID: mdl-37407687

Assuntos

Ferroptose; Neoplasias; Humanos; Di-Hidro-Orotato Desidrogenase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ferroptose / Neoplasias Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2023 Tipo de documento: Article

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