Neferine protected cardiomyocytes against hypoxia/oxygenation injury through SIRT1/Nrf2/HO-1 signaling.

Lu, Cheng; Jiang, Bing; Xu, Jie; Zhang, Xuan; Jiang, Nianxin

Lu, Cheng; Jiang, Bing; Xu, Jie; Zhang, Xuan; Jiang, Nianxin.

Afiliação

Lu C; Department of Cardiology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiang B; Department of Cardiology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xu J; Department of Cardiology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhang X; Department of Cardiology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Jiang N; Department of Cardiology, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.

J Biochem Mol Toxicol ; 37(8): e23398, 2023 Aug.

Article em En | MEDLINE | ID: mdl-37421224

Assuntos

Traumatismo por Reperfusão Miocárdica; Miócitos Cardíacos; Humanos; Miócitos Cardíacos/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Fator 2 Relacionado a NF-E2/metabolismo; Sirtuína 1/metabolismo; Transdução de Sinais; Estresse Oxidativo; Hipóxia/metabolismo; Apoptose; Traumatismo por Reperfusão Miocárdica/metabolismo

Palavras-chave

SIRT1/Nrf2; hypoxia/reoxygenation; ischemia/reperfusion; mitochondrial dysfunction; neferine; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Traumatismo por Reperfusão Miocárdica / Miócitos Cardíacos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biochem Mol Toxicol Ano de publicação: 2023 Tipo de documento: Article

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