Child with protein losing enteropathy as presentation of collagenous duodenitis and eosinophilic gastroenteritis.
Acta Gastroenterol Belg
; 86(2): 363-366, 2023.
Article
em En
| MEDLINE
| ID: mdl-37428172
ABSTRACT
Background:
Collagenous duodenitis and gastritis are rare histopathological findings in children. Patients andmethods:
We describe a four-year old girl, who presented with non-bloody diarrhea for two months and progressive edema with an albumin of 16g/dl.Results:
The diagnosis of a protein losing enteropathy was made. Extensive investigations withheld only an infectious cause of the protein losing enteropathy (cytomegalovirus and adenovirus). However, the patients still required repetitive albumin infusions 3.5 months after onset of symptoms without spontaneous recovery. Therefore, a new endoscopic work-up was performed. Duodenal biopsies revealed collagen deposition, in association with a high number of eosinophils and mast cells throughout different parts of the gastrointestinal tract.Conclusions:
The collagen deposition seems to be triggered by an eosinophilic gastrointestinal disorder. Treatment was started with amino acid-based formula, oral iron therapy, an antihistamine, and a proton pomp inhibitor that resulted in persistent normalization of serum albumin already after 1.5 weeks.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
3_ND
Base de dados:
MEDLINE
Assunto principal:
Enteropatias Perdedoras de Proteínas
/
Diarreia
/
Duodenite
/
Edema
/
Gastrite
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Child, preschool
/
Female
/
Humans
Idioma:
En
Revista:
Acta Gastroenterol Belg
Ano de publicação:
2023
Tipo de documento:
Article