Gas chromatography properties and mass spectrometry fragmentation of anabolic androgenic steroids in doping control.
Bioanalysis
; 15(12): 661-671, 2023 Jun.
Article
em En
| MEDLINE
| ID: mdl-37431827
ABSTRACT
Aim:
This study aimed to investigate the gas chromatographic properties and mass spectrometric fragmentations of anabolic androgenic steroids (AASs) after trimethylsilylated derivatization. Materials &methods:
A total of 113 AASs were analyzed through gas chromatography-mass spectrometry in the full-scan mode.Results:
New fragmentation pathways yielding m/z 129, 143 and 169 ions were analyzed. Based on the characteristics of the A-ring, seven classes of drugs were identified and analyzed.Conclusion:
The fragmentation pathway of a new classification of 4-en-3-hydroxyl was reported for the first time. The relationship between the chemical structures of AASs and their retention time, along with their molecular ion peak abundance, was also reported herein for the first time.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dopagem Esportivo
/
Anabolizantes
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Bioanalysis
Ano de publicação:
2023
Tipo de documento:
Article